Abstract—The 4th industrial revolution is affecting to medical and other industry. Recently, secure and reliable communication are required in medical or factory data transmission since ISM band is used and it occurs a lot of EMI Problems in existing RF communication. We use LC (Light Communication) to solve this problem in typical wireless environment. We use LED on the ceiling as the transmitter and PD in mobile device as the receiver for that. In this paper, we consider single carrier modulation for the connection between server and patients. We can also extend to Multi carrier Modulation such as DCO-OFDM for the high rate support. Based on the CIR model of the hospital or factory environment, the simulation is performed using OOK, 4-PAM, and 8-PAM to obtain link level performance. BER and the throughput are analyzed and compared in order to evaluate the potential use of VLC to the hospital ward or factory wirelss. It is shown that OOK can be applied to more secure cases and 8PAM can be better in considering the tradeoff between BER and throughput when the same transmitting power is used for that.