Abstract—The new product of wireless communication systems, the Fifth generation (5G), promises higher data rates and Spectrum Efficiency (SE) enhancements to support the communication of heterogeneous services. The Filtered-OFDM (F-OFDM) technique was proposed as the strongest candidate waveform for the physical layer in 5G to fulfill these requirements. In F-OFDM, the whole band is split into narrow sub-bands, each filtered by a digital Finite Impulse Response (FIR) filter with different specifications to increase the spectrum utilization and allow for asynchronous transmission. This paper proposes a novel F-OFDM design waveform for the first time with four sub-bands in equal and unequal sub-band sizes of seven kinds of window sinc filters and a variety of numerology designs to observe SE enhancement using Matlab-Simulink Software. Simulation results show that F-OFDM can reduce Out-Of-Band Emission (OOBE) and achieve SE of about (5%-6%) higher than conventional OFDM for equal and unequal sized sub-bands, respectively, by optimizing the guard band between the designed sub-bands, which achieves 5G guard band requirements.